Trial intelligence / Profile preview

In Vivo Circular RNA CAR-T Cell Therapy in R/R B-Cell Malignancies

NCT07774572Phase 1Recruiting

Sponsor
Ruijin Hospital
Start
May 2026
Primary completion
Mar 2027
Countries
1
01

Overview

Phase 1, open-label, single-arm trial in B cell lymphoma, chronic lymphocytic leukemia (CLL) and Waldenström macroglobulinemia (WM), sponsored by Ruijin Hospital. Primary endpoints: Incidence and severity of treatment-emergent adverse events at 24 weeks and Incidence of dose-limiting toxicities at 28 days. Started May 2026; status: recruiting.

02

Conditions

B cell lymphomachronic lymphocytic leukemia (CLL)Waldenström macroglobulinemia (WM)

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