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Pharmacokinetics, Biodistribution and Radiation Dosimetry of Granzyme-B Targeted [Cu-64]-Labeled PET Radiotracers in Healthy Volunteers

NCT07774650Phase 1Recruiting

Sponsor
Ratio Therapeutics
Start
Jul 2026
Primary completion
Dec 2026
Countries
1
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Overview

Phase 1, open-label trial of granzyme-B targeted [64Cu]-labeled PET radiotracer (2 arms), sponsored by Ratio Therapeutics. Primary endpoints: Maximum concentration of radiation in the blood at 24 hours, Time to maximum concentration in the blood at 24 hours and 6 more. Started Jul 2026; status: recruiting.

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Drugs

granzyme-B targeted [64Cu]-labeled PET radiotracer

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