Trial intelligence / Profile preview

TelOscope: CBX-663 in Advanced Cancers

NCT07779798Phase 1Recruiting

Sponsor
Crossbow Therapeutics
Start
Aug 2026
Primary completion
Jan 2028
Countries
1
01

Overview

Phase 1, open-label, single-arm trial of CBX-663 in acute myeloid leukemia (AML), myelodysplastic syndrome (MDS), chronic myelomonocytic leukemia (CMML) and 2 more, sponsored by Crossbow Therapeutics. Primary endpoints: Recommended Phase 2 Dose at 24 months, Dose Limiting Toxicities (DLTs), Treatment-Emergent Adverse Events (TEAEs) and Treatment-Related Adverse Events (TRAEs) and 32 more. Started Aug 2026; status: recruiting.

02

Drugs

CBX-663
03

Conditions

acute myeloid leukemia (AML)myelodysplastic syndrome (MDS)chronic myelomonocytic leukemia (CMML)solid tumorglioblastoma (GBM)

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