Trial intelligence / Profile preview

T-DXd + Azeliragon in T-DXd-Resistant HER2+ or HER2-Low Metastatic Breast Cancer

NCT07785856Phase 2Not yet recruiting

Sponsor
Houston Methodist Research Institute
Start
Dec 2026
Primary completion
Dec 2028
01

Overview

Phase 2, open-label, single-arm trial of azeliragon in breast cancer, sponsored by Houston Methodist Research Institute. Primary endpoints: Recommended Phase II Dose at 3 weeks and Objective Response Rate up to 2 years. Planned start Dec 2026; status: not yet recruiting.

02

Drugs

azeliragon
03

Conditions

breast cancer

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