Trial intelligence / Profile preview

MANTIS-RCC: Toripalimab-Axitinib Induction in TLS-Positive Advanced Non-Clear Cell Renal Carcinomas

NCT07816770Phase 2Not yet recruiting

Sponsor
Fudan University
Start
Sep 2026
Primary completion
Dec 2027
01

Overview

Phase 2, open-label, single-arm trial of toripalimab and axitinib in non-clear cell renal cell carcinoma (nccRCC) and renal medullary carcinoma (RMC), sponsored by Fudan University. Primary endpoints: Progression-Free Survival Rate at 24 weeks and Association Between the TLS Functional State Score and 24-Week Postoperative Progression-Free Survival. Planned start Sep 2026; status: not yet recruiting.

02

Drugs

toripalimabaxitinib
03

Conditions

non-clear cell renal cell carcinoma (nccRCC)renal medullary carcinoma (RMC)

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