Trial intelligence / Profile preview

MARGARET: Dexamethasone Premedication for Preventing ILD in Breast Cancer Patients on T-DXd

NCT07828054Phase 3Not yet recruiting

Sponsor
Mario Negri Institute for Pharmacological Research
Start
Dec 2026
Primary completion
Dec 2030
01

Overview

Phase 3, randomised, open-label trial of dexamethasone in interstitial lung disease (ILD) (2 arms), sponsored by Mario Negri Institute for Pharmacological Research. Primary endpoint: Cumulative incidence of Interstitial Lung Disease > Grade 1 at 12 months. Planned start Dec 2026; status: not yet recruiting.

02

Drugs

dexamethasone
03

Conditions

interstitial lung disease (ILD)

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