Trial intelligence / Profile preview

Rituximab, Pirtobrutinib, Lisaftoclax and Liposomal Mitoxantrone for Richter Syndrome

NCT07831395Phase 2Not yet recruiting

Sponsor
Institute of Hematology and Blood Diseases Hospital
Start
Sep 2026
Primary completion
Dec 2030
Countries
1
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Overview

Phase 2, open-label, single-arm trial of rituximab, pirtobrutinib, lisaftoclax and mitoxantrone hydrochloride liposome in Richter syndrome (RS), sponsored by Institute of Hematology and Blood Diseases Hospital. Primary endpoint: Complete Remission Rate at 12 weeks. Planned start Sep 2026; status: not yet recruiting.

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Drugs

rituximabpirtobrutiniblisaftoclaxmitoxantrone hydrochloride liposome
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Conditions

Richter syndrome (RS)

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