Trial intelligence / Profile preview

DMR-001 in CALR-mutant Myeloproliferative Neoplasms

NCT07849231Phase 1Recruiting

Sponsor
Damora Therapeutics
Start
Sep 2026
Primary completion
Jun 2030
Countries
2
01

Overview

Phase 1, open-label trial of DMR-001 in essential thrombocythemia (ET) and myelofibrosis (MF) (3 arms), sponsored by Damora Therapeutics. Primary endpoint: Safety and tolerability of DMR-001 & determine the MTD, RDE(s), and/or recommended Phase 2 dose(s) at 672 days. Started Sep 2026; status: recruiting.

02

Drugs

DMR-001
03

Conditions

essential thrombocythemia (ET)myelofibrosis (MF)

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