Trial intelligence / Profile preview

Bipolar Androgen Therapy Followed by Darolutamide vs. Standard of Care in mCRPC

NCT07852195Phase 3Not yet recruiting

Sponsor
ECOG-ACRIN Cancer Research Group
Start
Jan 2027
Primary completion
Mar 2029
01

Overview

Phase 3, randomised, open-label trial of testosterone cypionate and darolutamide in metastatic castration-resistant prostate cancer (mCRPC) (2 arms), sponsored by ECOG-ACRIN Cancer Research Group. Primary endpoints: Second progression-free survival up to 60 months, Overall survival up to 60 months and 1 more. Planned start Jan 2027; status: not yet recruiting.

02

Drugs

testosterone cypionatedarolutamide
03

Conditions

metastatic castration-resistant prostate cancer (mCRPC)

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