Trial intelligence / Profile preview

BActinium-2: [225Ac]Ac-AKY-2519 in B7-H3 Positive Solid Tumors

NCT07887971Phase 1Recruiting

Sponsor
Aktis Oncology
Start
Nov 2026
Primary completion
Dec 2028
Countries
1
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Overview

Phase 1, open-label, single-arm trial of AKY-2519 in non-small cell lung cancer (NSCLC), small cell lung cancer (SCLC), prostate cancer (PCa) and 3 more, sponsored by Aktis Oncology. Primary endpoints: Adverse Events at 30 days, Dose-Limiting Toxicity at 28 days and 1 more. Started Nov 2026; status: recruiting.

02

Drugs

AKY-2519
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Conditions

non-small cell lung cancer (NSCLC)small cell lung cancer (SCLC)prostate cancer (PCa)head and neck squamous cell carcinoma (HNSCC)Esophageal Squamous Cell Carcinoma (ESCC)

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