Trial intelligence / Profile preview

huCART19-IL18-CD428z Cells for HIV Patients With CD19+ Cancers

NCT07891468Phase 1Not yet recruiting

Sponsor
University of Pennsylvania
Start
Jan 2027
Primary completion
Dec 2042
Countries
1
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Overview

Phase 1, open-label, single-arm trial of huCART19-IL18-CD428z in non-Hodgkin lymphoma (NHL), chronic lymphocytic leukemia (CLL), acute lymphoblastic leukemia (ALL) and 1 more, sponsored by University of Pennsylvania. Primary endpoint: Safety at 15 years. Planned start Jan 2027; status: not yet recruiting.

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Drugs

huCART19-IL18-CD428z
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Conditions

non-Hodgkin lymphoma (NHL)chronic lymphocytic leukemia (CLL)acute lymphoblastic leukemia (ALL)Richter's transformation (RT)

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