Trial intelligence / Profile preview

GD2IL18CART + Bevacizumab in Relapsed/Refractory GD2+ Solid Cancers

NCT07897968Phase 1Not yet recruiting

Sponsor
Universität Münster
Start
Oct 2027
Primary completion
Sep 2031
Countries
1
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Overview

Phase 1, open-label, single-arm trial of GD2-IL18-CAR-T in neuroblastoma, Ewing sarcoma and osteosarcoma (OS), sponsored by Universität Münster. Primary endpoints: Incidence and severity of adverse events at 12 months, Dose-limiting toxicities at 28 days and 2 more. Planned start Oct 2027; status: not yet recruiting.

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Drugs

GD2-IL18-CAR-T
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Conditions

neuroblastomaEwing sarcomaosteosarcoma (OS)

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