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Regenerative Endodontic Treatment Using i-PRF vs Conventional Root Canal Treatment in Mature Necrotic Anterior Teeth

NCT07913399Not yet recruiting

Sponsor
Istanbul Medipol University
Start
Nov 2026
Primary completion
Jul 2027
01

Overview

Randomised trial of platelet rich fibrin in apical periodontitis (AP) and pulp necrosis (3 arms), sponsored by Istanbul Medipol University. Primary endpoints: Periapical Radiographic Healing Evaluated by Modified Periapical Index at 6 months and Clinical Treatment Success Rate at 6 months. Planned start Nov 2026; status: not yet recruiting.

02

Drugs

platelet rich fibrin
03

Conditions

apical periodontitis (AP)pulp necrosis

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