Trial intelligence / Profile preview

Early minimization of maintenance immunosuppression after renal transplantation

NL-OMON22724Suspended

Sponsor
Novartis
Start
Jan 2005
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Small Molecules, Peptides
Countries
1
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Overview

Randomised, open-label trial in kidney transplant, kidney failure and Chronic Allograft Kidney Disease (CKaD) comparing Everolimus + prednisolone maintenance, Mycophenolate sodium + prednisolone maintenance and Ciclosporin + prednisolone reference therapy (3 arms). Primary endpoints: Inflammation and fibrosis in renal biopsies, Arteriolar hyalinosis in renal biopsies and 1 more. Started Jan 2005; status: suspended.

02

Drugs

everolimusmycophenolate sodiumcyclosporineprednisolone
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Conditions

kidney transplantkidney failureChronic Allograft Kidney Disease (CKaD)

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