Trial intelligence / Profile preview

R-PECC followed by 90Y-ibritumomab tiuxetan consolidation in relapsed or refractory aggressive B-cell non-Hodgkin lymphoma

NL-OMON24909Phase 2Not yet recruiting

Sponsor
HOVON
Start
Aug 2008
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Small Molecules
Countries
1
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Overview

Phase 2, open-label, single-arm trial of ibritumomab tiuxetan, rituximab, lomustine, etoposide, chlorambucil and 1 more in mature B-cell lymphoma, follicular lymphoma (FL) and diffuse large B-cell lymphoma (DLBCL), sponsored by HOVON. Primary endpoints: Incidence of grade 3 or higher adverse events after 90Y-ibritumomab tiuxetan and Failure-free survival from start of 90Y-ibritumomab tiuxetan. Planned start Aug 2008; status: not yet recruiting.

02

Drugs

ibritumomab tiuxetanrituximablomustineetoposidechlorambucil
03

Conditions

mature B-cell lymphomafollicular lymphoma (FL)diffuse large B-cell lymphoma (DLBCL)

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