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Acute oral versus intravenous sodium loading in type 2 diabetes and diabetic kidney disease with GLP-1 agonist challenge

NL-OMON27521Recruiting

Start
Jan 2020
Modality
Recombinant Proteins and Enzymes, Peptides
Countries
1
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Overview

Open-label trial of Glucagon-like peptide 1 and sodium chloride in type 2 diabetes mellitus (T2DM), diabetic glomerulosclerosis and chronic kidney disease (CKD) (3 arms), sponsored by None. Primary endpoints: Cumulative urinary sodium balance at 24 hours and Fractional natriuresis at 24 hours. Started Jan 2020; status: recruiting.

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Drugs

Glucagon-like peptide 1sodium chloride
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Conditions

type 2 diabetes mellitus (T2DM)diabetic glomerulosclerosischronic kidney disease (CKD)

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