Trial intelligence / Profile preview

WT1 mRNA-transfected autologous dendritic cell vaccination in acute myeloid leukemia

NL-OMON27609Phase 1Active, not recruiting

Sponsor
Antwerp University Hospital
Start
Mar 2005
Modality
Dendritic Cell Vaccines → Immune Effector Cells → Other Cell Types → Cell Therapies, Vaccines & Immunotherapeutics, mRNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics
Countries
1
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Overview

Phase 1, open-label trial of WT1 mRNA-loaded autologous monocyte-derived dendritic cells in acute myeloid leukemia (AML) and myelodysplastic syndrome with excess blasts (MDS-EB), sponsored by Antwerp University Hospital. Primary endpoint: Safety of multiple dendritic cell injections. Started Mar 2005; status: active, not recruiting.

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Drugs

WT1 mRNA-loaded autologous monocyte-derived dendritic cells
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Conditions

acute myeloid leukemia (AML)myelodysplastic syndrome with excess blasts (MDS-EB)

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