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Single-dose crossover study of valproic acid, levetiracetam, and lorazepam effects on cortical excitability measured by TMS-EEG and TMS-EMG in healthy volunteers
NL-OMON28239Completed
- Sponsor
- Centre for Human Drug Research
- Start
- Sep 2017
- Modality
- Small Molecules
- Countries
- 1
01
Overview
Randomised, double-blind trial of valproic acid, levetiracetam and lorazepam in epilepsy (4 arms), sponsored by Centre for Human Drug Research. Primary endpoints: Resting motor threshold, Peak-to-peak MEP amplitude and 3 more. Started Sep 2017; status: completed.
02
Drugs
valproic acidlevetiracetamlorazepam
03
Conditions
epilepsy
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