Trial intelligence / Profile preview

Rituximab plus CHOP-14 versus CHOP-14 alone in elderly CD20-positive non-Hodgkin lymphoma

NL-OMON28411Phase 3Active, not recruiting

Sponsor
HOVON
Start
Nov 2001
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules
Countries
1
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Overview

Phase 3, randomised, open-label trial of rituximab, cyclophosphamide, doxorubicin, vincristine, prednisone and 1 more in non-Hodgkin lymphoma (NHL), mantle cell lymphoma (MCL), follicular lymphoma (FL) and 1 more (2 arms), sponsored by HOVON. Primary endpoint: Event-free survival. Started Nov 2001; status: active, not recruiting.

02

Drugs

rituximabcyclophosphamidedoxorubicinvincristineprednisone
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Conditions

non-Hodgkin lymphoma (NHL)mantle cell lymphoma (MCL)follicular lymphoma (FL)diffuse large B-cell lymphoma (DLBCL)

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