Trial intelligence / Profile preview

PROOF study of personalized chemotherapy selection from pleural fluid tumor cell drug profiling

NL-OMON28874Phase 2Not yet recruiting

Sponsor
Netherlands Cancer Institute
Start
Jun 2014
Modality
DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, open-label, single-arm trial of vinorelbine, gemcitabine, pemetrexed, oxaliplatin, doxorubicin and 2 more in pleural mesothelioma and non-small cell lung cancer (NSCLC), sponsored by Netherlands Cancer Institute. Primary endpoint: Accuracy of the drug profiling method. Planned start Jun 2014; status: not yet recruiting.

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Drugs

vinorelbinegemcitabinepemetrexedoxaliplatindoxorubicin
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Conditions

pleural mesotheliomanon-small cell lung cancer (NSCLC)

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