Trial intelligence / Profile preview

Phase I study of gemcitabine + carboplatin + sorafenib in advanced solid tumors

NL-OMON31053Phase 1Not yet recruiting

Sponsor
Netherlands Cancer Institute
Start
Sep 2007
Modality
DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules
Countries
1
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Overview

Phase 1, open-label, single-arm trial of gemcitabine, carboplatin and sorafenib in Nonhematologic neoplasms, non-small cell lung cancer (NSCLC), bladder cancer and 2 more, sponsored by Netherlands Cancer Institute. Primary endpoints: Safety and tolerability and Maximum tolerated dose and dose-limiting toxicity. Planned start Sep 2007; status: not yet recruiting.

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Drugs

gemcitabinecarboplatinsorafenib
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Conditions

Nonhematologic neoplasmsnon-small cell lung cancer (NSCLC)bladder cancerpancreatic cancer (PC)ovarian cancer

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