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Laromustine added to standard induction chemotherapy for previously untreated AML or high-risk RAEB
NL-OMON31859Phase 3Active, not recruiting
- Sponsor
- HOVON
- Start
- Dec 2008
- Modality
- Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules
- Countries
- 1
01
Overview
Phase 3, randomised, open-label trial of laromustine in acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) (2 arms), sponsored by HOVON. Primary endpoints: Dose-limiting toxicity and duration of myelosuppression and Event-free survival. Started Dec 2008; status: active, not recruiting.
02
Drugs
laromustine
03
Conditions
acute myeloid leukemia (AML)myelodysplastic syndrome (MDS)
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