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TMC278-methadone drug-drug interaction study in adults on stable methadone maintenance
NL-OMON32622Phase 1Active, not recruiting
- Sponsor
- Tibotec
- Start
- Aug 2008
- Modality
- Small Molecules, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules
- Countries
- 1
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Overview
Phase 1, open-label, single-arm trial of rilpivirine and methadone in human immunodeficiency virus infection (HIV) and opioid use disorder (OUD), sponsored by Tibotec. Primary endpoints: Steady-state pharmacokinetics of R-methadone and S-methadone, Pharmacodynamic effects of methadone therapy and 2 more. Started Aug 2008; status: active, not recruiting.
02
Drugs
rilpivirinemethadone
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Conditions
human immunodeficiency virus infection (HIV)opioid use disorder (OUD)
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