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Pharmacokinetics of sedative, analgesic, anticonvulsant, and antiarrhythmic drugs during therapeutic hypothermia in asphyxiated neonates
NL-OMON33059Active, not recruiting
- Sponsor
- University Medical Center Utrecht
- Start
- Nov 2009
- Modality
- Small Molecules, Allosteric Modulators → Classical Binding Small Molecules → Small Molecules
- Countries
- 1
01
Overview
Open-label, single-arm trial of midazolam, morphine, phenobarbital and lidocaine in hypoxic-ischemic encephalopathy (HIE) and asphyxia neonatorum, sponsored by University Medical Center Utrecht. Primary endpoints: Population pharmacokinetic profiles of midazolam, Population pharmacokinetic profiles of morphine and 2 more. Started Nov 2009; status: active, not recruiting.
02
Drugs
midazolammorphinephenobarbitallidocaine
03
Conditions
hypoxic-ischemic encephalopathy (HIE)asphyxia neonatorum
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