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T-cell homeostasis after ATG-induced lymphocytopenia in renal transplant patients using in vivo deuterated water labeling
NL-OMON35541Active, not recruiting
- Sponsor
- Amsterdam University Medical Center
- Start
- Oct 2011
- Modality
- Recombinant Proteins and Enzymes, Antibody-Based Therapeutics, Small Molecules
- Countries
- 1
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Overview
Open-label trial of antithymocyte globulin rabbit and deuterated water in kidney allograft rejection and lymphocytopenia (3 arms), sponsored by Amsterdam University Medical Center. Primary endpoints: 2H2O incorporation into DNA of naive CD4+ and CD8+ T cells and Production rate and half-life of naive CD4+ and CD8+ T cells. Started Oct 2011; status: active, not recruiting.
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Drugs
antithymocyte globulin rabbitdeuterated water
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Conditions
kidney allograft rejectionlymphocytopenia
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