IV sildenafil added to inhaled nitric oxide for neonates with PPHN or hypoxic respiratory failure

Phase 3, randomised, double-blind trial in persistent pulmonary hypertension of the newborn (PPHN) and hypoxemic respiratory failure comparing IV sildenafil + inhaled nitric oxide with Placebo + inhaled nitric oxide (2 arms). Primary endpoints: Time on inhaled nitric oxide after initiation of IV study drug in subjects without treatment failure and Treatment failure rate. Started Sep 2013; status: active, not recruiting.