Early prophylactic CD4-positive donor lymphocyte infusion after T-cell-depleted unrelated allogeneic stem cell transplantation

Phase 2, open-label, single-arm trial of CD4-positive donor lymphocytes in acute myeloid leukemia (AML), myelodysplastic syndrome (MDS), acute lymphoblastic leukemia (ALL) and 5 more, sponsored by Leiden University Medical Center. Primary endpoint: Circulating naive CD4-positive lymphocytes. Started Oct 2012; status: active, not recruiting.