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Effects of cholestasis on probe-drug pharmacokinetics before and after biliary drainage
NL-OMON38889Withdrawn
- Sponsor
- Amsterdam University Medical Center
- Start
- Jul 2013
- Modality
- Small Molecules
- Countries
- 1
01
Overview
Open-label, single-arm trial of caffeine, warfarin, omeprazole, metoprolol and midazolam, sponsored by Amsterdam University Medical Center. Primary endpoint: Difference in AUC for each probe drug before versus after drainage. Planned start Jul 2013; status: withdrawn.
02
Drugs
caffeinewarfarinomeprazolemetoprololmidazolam
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