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Effect of broad-spectrum antibiotics and gut microbiota depletion on immune responses during experimental human endotoxemia
NL-OMON38933Not yet recruiting
- Sponsor
- Amsterdam University Medical Center
- Start
- Jun 2014
- Modality
- Antimicrobial Peptides → Native Peptides → Peptides, Cyclic Peptides → Modified Peptides → Peptides, Small Molecules
- Countries
- 1
01
Overview
Randomised, open-label trial of ciprofloxacin, vancomycin, metronidazole and lipopolysaccharide endotoxin in endotoxemia (2 arms), sponsored by Amsterdam University Medical Center. Primary endpoint: Cytokine production in blood. Planned start Jun 2014; status: not yet recruiting.
02
Drugs
ciprofloxacinvancomycinmetronidazolelipopolysaccharide endotoxin
03
Conditions
endotoxemia
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