Trial intelligence / Profile preview

Tosedostat added to standard induction chemotherapy for elderly or very poor risk AML

NL-OMON39280Phase 2Recruiting

Sponsor
HOVON
Start
Sep 2010
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Allosteric Modulators → Classical Binding Small Molecules → Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules
Countries
1
01

Overview

Phase 2, randomised, open-label trial of tosedostat in acute myeloid leukemia (AML) and myelodysplastic syndrome with excess blasts (MDS-EB) (6 arms), sponsored by HOVON. Primary endpoints: Dose-limiting toxicity and Complete remission rate. Started Sep 2010; status: recruiting.

02

Drugs

tosedostat
03

Conditions

acute myeloid leukemia (AML)myelodysplastic syndrome with excess blasts (MDS-EB)

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