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Central GLP-1 effects on brain satiety and reward responses in obesity and type 2 diabetes

NL-OMON39550Active, not recruiting

Sponsor
Vrije University Medical Center
Start
Oct 2011
Modality
Peptides, Recombinant Proteins and Enzymes
Countries
1
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Overview

Randomised, open-label trial of liraglutide, exendin 9-39 and insulin glargine in type 2 diabetes mellitus (T2DM) and obesity (4 arms), sponsored by Vrije University Medical Center. Primary endpoints: Endogenous GLP-1 effect on CNS satiety and reward circuitry, Difference between obese type 2 diabetes and lean healthy subjects in endogenous GLP-1 effect and 2 more. Started Oct 2011; status: active, not recruiting.

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Drugs

liraglutideexendin 9-39insulin glargine
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Conditions

type 2 diabetes mellitus (T2DM)obesity

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