Trial intelligence / Profile preview

Phase III trial of grazoprevir + elbasvir with or without ribavirin in prior peginterferon/ribavirin failures with chronic hepatitis C

NL-OMON40780Phase 3Active, not recruiting

Sponsor
Merck & Co.
Start
Jun 2014
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules
Countries
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Overview

Phase 3, randomised trial of grazoprevir, elbasvir and ribavirin in hepatitis C virus infection (4 arms), sponsored by Merck & Co. Primary endpoints: SVR12 and Safety and tolerability. Started Jun 2014; status: active, not recruiting.

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Drugs

grazoprevirelbasvirribavirin
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Conditions

hepatitis C virus infection

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