Trial intelligence / Profile preview

Olaparib drug-drug interaction study with anastrozole, letrozole, and tamoxifen in advanced solid tumors

NL-OMON40826Phase 1Active, not recruiting

Sponsor
AstraZeneca
Start
Oct 2014
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules, Small Molecules
Countries
1
01

Overview

Phase 1, open-label trial of olaparib, tamoxifen, anastrozole and letrozole in Nonhematologic neoplasms (3 cohorts), sponsored by AstraZeneca. Primary endpoints: Steady-state maximum plasma concentration, Steady-state area under the plasma concentration-time curve over the dosing interval and 1 more. Started Oct 2014; status: active, not recruiting.

02

Drugs

olaparibtamoxifenanastrozoleletrozole
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Conditions

Nonhematologic neoplasms

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