Trial intelligence / Profile preview

Phase I Hespecta vaccine study in HPV16-positive oropharyngeal squamous cell cancer after curative treatment

NL-OMON41192Phase 1Recruiting

Sponsor
Leiden University Medical Center
Start
Jan 2016
Modality
Peptide-based Cancer Vaccines → Cancer Vaccines → Therapeutic Vaccines → Vaccines & Immunotherapeutics, Peptides
Countries
1
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Overview

Phase 1, open-label trial of synthetic human papillomavirus 16 E6 peptide in oropharyngeal squamous cell carcinoma (OPSCC) and head and neck cancer (HNC) (4 arms), sponsored by Leiden University Medical Center. Primary endpoint: Biological activity: induction of HPV16 E6-specific T-cell immunity. Started Jan 2016; status: recruiting.

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Drugs

synthetic human papillomavirus 16 E6 peptide
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Conditions

oropharyngeal squamous cell carcinoma (OPSCC)head and neck cancer (HNC)

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