Trial intelligence / Profile preview

Phase 1 first-in-human study of RG2459 alone and with simeprevir in healthy volunteers and patients with chronic hepatitis C

NL-OMON41383Phase 1Active, not recruiting

Sponsor
Regulus Therapeutics
Start
Feb 2014
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Allosteric Modulators → Classical Binding Small Molecules → Small Molecules, Reversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules
Countries
1
01

Overview

Phase 1, randomised, double-blind trial of RG-101 and simeprevir in hepatitis C virus infection (4 arms), sponsored by Regulus Therapeutics. Primary endpoint: Safety and tolerability. Started Feb 2014; status: active, not recruiting.

02

Drugs

RG-101simeprevir
03

Conditions

hepatitis C virus infection

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