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Clofarabine added to prephase and consolidation therapy in adult acute lymphoblastic leukemia
NL-OMON41476Phase 3Active, not recruiting
- Sponsor
- HOVON
- Start
- Oct 2009
- Modality
- Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules
- Countries
- 1
01
Overview
Phase 3, randomised, open-label trial of clofarabine in acute lymphoblastic leukemia (ALL) and T-lymphoblastic lymphoma (T-LBL) (2 arms), sponsored by HOVON. Primary endpoints: Feasibility of clofarabine added to standard prephase chemotherapy and Event-free survival. Started Oct 2009; status: active, not recruiting.
02
Drugs
clofarabine
03
Conditions
acute lymphoblastic leukemia (ALL)T-lymphoblastic lymphoma (T-LBL)
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