Trial intelligence / Profile preview

Phase 1 study of ABT-414 in glioblastoma multiforme

NL-OMON41552Phase 1Active, not recruiting

Sponsor
AbbVie Inc.
Start
Jan 2014
Modality
Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics, Classical Binding Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules
Countries
1
01

Overview

Phase 1, open-label trial of depatuxizumab mafodotin in glioblastoma (GBM) (6 arms), sponsored by AbbVie Inc. Primary endpoints: Safety of ABT-414 with radiation and temozolomide, Maximum tolerated dose and 6 more. Started Jan 2014; status: active, not recruiting.

02

Drugs

depatuxizumab mafodotin
03

Conditions

glioblastoma (GBM)

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