Trial intelligence / Profile preview

AURA3: AZD9291 versus platinum-pemetrexed chemotherapy in EGFR T790M-positive advanced non-small cell lung cancer after prior EGFR-TKI

NL-OMON42148Phase 3Completed

Sponsor
AstraZeneca
Start
Oct 2014
Modality
Small Molecules, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Countries
1
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Overview

Phase 3, randomised, open-label trial of osimertinib, pemetrexed, carboplatin and cisplatin in non-small cell lung cancer (NSCLC) (2 arms), sponsored by AstraZeneca. Primary endpoint: Progression-free survival. Started Oct 2014; status: completed.

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Drugs

osimertinibpemetrexedcarboplatincisplatin
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Conditions

non-small cell lung cancer (NSCLC)

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