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Phase I study of metformin and chloroquine in IDH1/2-mutated glioma, intrahepatic cholangiocarcinoma, or chondrosarcoma
NL-OMON42677Phase 1Active, not recruiting
- Sponsor
- Amsterdam University Medical Center
- Start
- Nov 2015
- Modality
- Small Molecules
- Countries
- 1
01
Overview
Phase 1, open-label, single-arm trial of metformin and chloroquine in glioma, intrahepatic cholangiocarcinoma (ICC) and chondrosarcoma, sponsored by Amsterdam University Medical Center. Primary endpoints: Maximum tolerated dose and Recommended dose. Started Nov 2015; status: active, not recruiting.
02
Drugs
metforminchloroquine
03
Conditions
gliomaintrahepatic cholangiocarcinoma (ICC)chondrosarcoma
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