Trial intelligence / Profile preview

ABT-494 monotherapy versus methotrexate in methotrexate-naive rheumatoid arthritis

NL-OMON43652Phase 3Withdrawn

Sponsor
AbbVie Inc.
Start
Nov 2015
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Nucleic Acid-Directed Small Molecules → Small Molecules
Countries
1
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Overview

Phase 3, randomised, double-blind trial of upadacitinib and methotrexate in rheumatoid arthritis (RA) (3 arms), sponsored by AbbVie Inc. Primary endpoints: ACR50 response at Week 24, Clinical remission at Week 24 and 2 more. Planned start Nov 2015; status: withdrawn.

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Drugs

upadacitinibmethotrexate
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Conditions

rheumatoid arthritis (RA)

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