Trial intelligence / Profile preview

Therapeutic drug monitoring of asparaginase and methotrexate metabolism in childhood acute lymphoblastic leukemia

NL-OMON44473Phase 4Active, not recruiting

Sponsor
Erasmus MC
Start
Mar 2015
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Nucleic Acid-Directed Small Molecules → Small Molecules
Countries
1
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Overview

Phase 4, randomised, open-label trial of pegaspargase and methotrexate in acute lymphoblastic leukemia (ALL) (2 arms), sponsored by Erasmus MC. Primary endpoints: PEGaspargase clearance, Inter-patient variability in clearance and 6 more. Started Mar 2015; status: active, not recruiting.

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Drugs

pegaspargasemethotrexate
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Conditions

acute lymphoblastic leukemia (ALL)

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