Trial intelligence / Profile preview

Radiolabeled AL-335 metabolism and excretion study alone and with odalasvir plus simeprevir

NL-OMON44638Phase 1Withdrawn

Sponsor
Janssen Pharmaceutical
Start
Jul 2017
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Allosteric Modulators → Classical Binding Small Molecules → Small Molecules, Reversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules
Countries
1
01

Overview

Phase 1, open-label trial of adafosbuvir, odalasvir and simeprevir in hepatitis C virus infection (2 arms), sponsored by Janssen Pharmaceutical. Primary endpoint: Metabolic pathways and routes of excretion of AL-335. Planned start Jul 2017; status: withdrawn.

02

Drugs

adafosbuvirodalasvirsimeprevir
03

Conditions

hepatitis C virus infection

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