Trial intelligence / Profile preview

Itraconazole interaction study with AZD9291 in EGFR-mutant NSCLC after prior EGFR TKI

NL-OMON45155Phase 1Recruiting

Sponsor
AstraZeneca
Start
Jan 2015
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Small Molecules
Countries
1
01

Overview

Phase 1, open-label trial of osimertinib and itraconazole in non-small cell lung cancer (NSCLC) (2 arms), sponsored by AstraZeneca. Primary endpoint: Effect of itraconazole on AZD9291 exposure. Started Jan 2015; status: recruiting.

02

Drugs

osimertinibitraconazole
03

Conditions

non-small cell lung cancer (NSCLC)

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