Trial intelligence / Profile preview

Pembrolizumab with or without platinum-based chemotherapy versus chemotherapy for advanced or metastatic urothelial carcinoma

NL-OMON45288Phase 3Active, not recruiting

Sponsor
Merck & Co.
Start
Jul 2017
Modality
Small Molecules, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Countries
1
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Overview

Phase 3, randomised, open-label trial of pembrolizumab, cisplatin, carboplatin and gemcitabine in transitional cell carcinoma (TCC) and bladder cancer (3 arms), sponsored by Merck & Co. Primary endpoints: Progression-free survival and Overall survival. Started Jul 2017; status: active, not recruiting.

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Drugs

pembrolizumabcisplatincarboplatingemcitabine
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Conditions

transitional cell carcinoma (TCC)bladder cancer

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