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ADH-independent urine concentration with sildenafil, metformin, or simvastatin in healthy volunteers
NL-OMON45483Active, not recruiting
- Sponsor
- Radboud University Medical Center
- Start
- Apr 2017
- Modality
- Small Molecules
- Countries
- 1
01
Overview
Open-label trial of sildenafil, metformin and simvastatin in Arginine Vasopressin Resistance (AVP-R) and diabetes insipidus (DI) (3 arms), sponsored by Radboud University Medical Center. Primary endpoint: Minimal urine osmolality after water loading. Started Apr 2017; status: active, not recruiting.
02
Drugs
sildenafilmetforminsimvastatin
03
Conditions
Arginine Vasopressin Resistance (AVP-R)diabetes insipidus (DI)
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