Trial intelligence / Profile preview

KEYNOTE-181 pembrolizumab versus chemotherapy in previously treated advanced esophageal cancer

NL-OMON45950Phase 3Active, not recruiting

Sponsor
Merck & Co.
Start
Dec 2015
Modality
Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes
Countries
1
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Overview

Phase 3, randomised, open-label trial of pembrolizumab in esophageal cancer, esophageal adenocarcinoma (EAC), Esophageal Squamous Cell Carcinoma (ESCC) and 1 more, sponsored by Merck & Co. Primary endpoints: Overall Survival in esophageal squamous cell carcinoma, Overall Survival in PD-L1 CPS >=10 population and 1 more. Started Dec 2015; status: active, not recruiting.

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Drugs

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Conditions

esophageal canceresophageal adenocarcinoma (EAC)Esophageal Squamous Cell Carcinoma (ESCC)gastroesophageal junction adenocarcinoma

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