Trial intelligence / Profile preview

Olaparib plus abiraterone versus placebo plus abiraterone in first-line metastatic castration-resistant prostate cancer

NL-OMON45999Phase 3Active, not recruiting

Sponsor
AstraZeneca
Start
Apr 2019
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Small Molecules
Countries
1
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Overview

Phase 3, randomised, double-blind trial in metastatic castration-resistant prostate cancer (mCRPC) and prostate cancer (PCa) comparing Olaparib + abiraterone + prednisone with Placebo + abiraterone + prednisone (2 arms). Primary endpoint: Radiographic progression-free survival. Started Apr 2019; status: active, not recruiting.

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Drugs

olaparibabirateroneprednisone
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Conditions

metastatic castration-resistant prostate cancer (mCRPC)prostate cancer (PCa)

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