Trial intelligence / Profile preview

Azacitidine plus durvalumab versus azacitidine alone in previously untreated higher-risk MDS or elderly AML

NL-OMON46021Phase 2Withdrawn

Sponsor
Celgene Corporation
Start
Feb 2016
Modality
PD-1/PD-L1 Inhibitors → Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, randomised, open-label trial in myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML) comparing Azacitidine + durvalumab with Azacitidine alone (2 arms). Primary endpoint: Overall response rate. Planned start Feb 2016; status: withdrawn.

02

Drugs

durvalumabazacitidine
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Conditions

myelodysplastic syndrome (MDS)acute myeloid leukemia (AML)

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