Trial intelligence / Profile preview

Tepotinib + gefitinib versus platinum-pemetrexed in MET-positive, EGFR-mutant NSCLC after acquired resistance to EGFR-TKI

NL-OMON46330Phase 2Withdrawn

Sponsor
Merck & Co.
Start
Dec 2016
Modality
Small Molecules, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Countries
1
01

Overview

Phase 2, randomised, open-label trial of tepotinib, gefitinib, pemetrexed, cisplatin and carboplatin in non-small cell lung cancer (NSCLC) (3 arms), sponsored by Merck & Co. Primary endpoint: Progression-free survival. Planned start Dec 2016; status: withdrawn.

02

Drugs

tepotinibgefitinibpemetrexedcisplatincarboplatin
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Conditions

non-small cell lung cancer (NSCLC)

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