Trial intelligence / Profile preview

Anetumab ravtansine drug-drug interaction and ECG study with itraconazole in mesothelin-expressing advanced solid cancers

NL-OMON46366Phase 1Completed

Sponsor
Bayer
Start
Dec 2017
Modality
Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 1, open-label trial of anetumab ravtansine in mesothelioma, ovarian cancer, pancreatic cancer (PC) and 6 more (2 arms), sponsored by Bayer. Primary endpoints: ECG parameters, AUC from zero to infinity after first dose and 2 more. Started Dec 2017; status: completed.

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Drugs

anetumab ravtansine
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Conditions

mesotheliomaovarian cancerpancreatic cancer (PC)triple-negative breast cancer (TNBC)non-small cell lung cancer (NSCLC)

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